SCI Patient Handout Library

Orthostatic Hypotension

When sitting up makes you feel faint โ€” and how to manage it.

What is it?

Orthostatic hypotension (OH) is a drop in your blood pressure when you go from lying flat to sitting up or standing. After a spinal cord injury, your body cannot tighten the blood vessels in your legs and belly fast enough, so blood pools below your injury. Less blood reaches your brain. You feel dizzy, lightheaded, or pass out.

OH is most common in the first weeks after injury, but it can stick around or come back when you are sick, dehydrated, or after a hot shower.

How you might feel

What you can do

๐Ÿ’Š Medicines if lifestyle steps are not enough

  • Midodrine 5โ€“10 mg by mouth, 30 minutes before getting up. Wears off in 4 hours. Do not take within 4 hours of bedtime โ€” you can spike your BP while lying down.
  • Fludrocortisone 0.1 mg by mouth in the morning. Builds up over a week.
  • Pyridostigmine 30โ€“60 mg up to three times a day.

Ask before you take any new medicine, even over-the-counter cold medicine.

๐Ÿ“ž Call your doctor if

  • You pass out (lose consciousness).
  • Episodes are getting more frequent.
  • New chest pain or trouble breathing.

At your next clinic visit

Bring a 1โ€“2 week home blood pressure log: lying, sitting, standing, with the time of any new medicine dose. Patterns guide treatment.


Education only. Not medical advice. If you have a clinical question, talk to your rehab team. For emergencies call 911.